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Pten (phosphatase and tensin homologue gene) haploinsufficiency promotes insulin hypersensitivity
AIMS/HYPOTHESIS: Insulin controls glucose metabolism via multiple signalling pathways, including the phosphatidylinositol 3-kinase (PI3K) pathway in muscle and adipose tissue. The protein/lipid phosphatase Pten (phosphatase and tensin homologue deleted on chromosome 10) attenuates PI3K signalling by...
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Main Authors: | , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Springer-Verlag
2006
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1781097/ https://ncbi.nlm.nih.gov/pubmed/17195063 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-006-0531-x |
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