Pten (phosphatase and tensin homologue gene) haploinsufficiency promotes insulin hypersensitivity

AIMS/HYPOTHESIS: Insulin controls glucose metabolism via multiple signalling pathways, including the phosphatidylinositol 3-kinase (PI3K) pathway in muscle and adipose tissue. The protein/lipid phosphatase Pten (phosphatase and tensin homologue deleted on chromosome 10) attenuates PI3K signalling by...

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Main Authors: Wong, J. T., Kim, P. T. W., Peacock, J. W., Yau, T. Y., Mui, A. L.-F., Chung, S. W., Sossi, V., Doudet, D., Green, D., Ruth, T. J., Parsons, R., Verchere, C. B., Ong, C. J.
格式: Artigo
語言:Inglês
出版: Springer-Verlag 2006
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1781097/
https://ncbi.nlm.nih.gov/pubmed/17195063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-006-0531-x
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