Negative Regulation of Myofibroblast Differentiation by PTEN (Phosphatase and Tensin Homolog Deleted on Chromosome 10)

Rationale: Myofibroblasts are primary effector cells in idiopathic pulmonary fibrosis (IPF). Defining mechanisms of myofibroblast differentiation may be critical to the development of novel therapeutic agents. Objective: To show that myofibroblast differentiation is regulated by phosphatase and tens...

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Detalhes bibliográficos
Main Authors: White, Eric S., Atrasz, Rachelle G., Hu, Biao, Phan, Sem H., Stambolic, Vuk, Mak, Tak W., Hogaboam, Cory M., Flaherty, Kevin R., Martinez, Fernando J., Kontos, Christopher D., Toews, Galen B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2006
Assuntos:
F. Interstitial Lung Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1434700/
https://ncbi.nlm.nih.gov/pubmed/16179636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200507-1058OC
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