Muscle-Specific Pten Deletion Protects against Insulin Resistance and Diabetes

Pten (phosphatase with tensin homology), a dual-specificity phosphatase, is a negative regulator of the phosphoinositide 3-kinase (PI3K)/Akt signaling pathway. Pten regulates a vast array of biological functions including growth, metabolism, and longevity. Although the PI3K/Akt pathway is a key dete...

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Bibliographic Details
Published in:Mol Cell Biol
Main Authors: Wijesekara, Nadeeja, Konrad, Daniel, Eweida, Mohamed, Jefferies, Craig, Liadis, Nicole, Giacca, Adria, Crackower, Mike, Suzuki, Akira, Mak, Tak W., Kahn, C. Ronald, Klip, Amira, Woo, Minna
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2005
Subjects:
Signal Transduction
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC544010/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15657439/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.25.3.1135-1145.2005
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