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Unusual Features of Self-Peptide/MHC Binding by Autoimmune T Cell Receptors
Structural studies on T cell receptors (TCRs) specific for foreign antigens demonstrated a remarkably similar topology characterized by a central, diagonal TCR binding mode that maximizes interactions with the MHC bound peptide. However, three recent structures involving autoimmune TCRs demonstrated...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3417822/ https://ncbi.nlm.nih.gov/pubmed/16226501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2005.09.009 |
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