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T cell Receptor Recognition of Self and Foreign Antigens in the Induction of Autoimmunity

The Major Histocompatibility Complex (MHC) on human chromosome 6 represents the most important genetic locus for a number of common human autoimmune diseases. Specific alleles that differ from closely related alleles by only one or a few amino acids in the peptide binding groove are frequently stron...

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Detalhes bibliográficos
Main Authors: Wucherpfennig, Kai W., Sethi, Dhruv
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073734/
https://ncbi.nlm.nih.gov/pubmed/21306912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smim.2011.01.007
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