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Structural Alterations in peptide–MHC Recognition by Self-reactive T cell Receptors
The crystal structures of five autoimmune T cell receptor (TCR)–peptide–MHC complexes reveal substantial structural alterations compared to anti-microbial TCRs. The two human TCRs bind their self-peptide–MHC ligands with an altered topology, while the three mouse receptors recognize a self-peptide t...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2787854/ https://ncbi.nlm.nih.gov/pubmed/19699075 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2009.07.008 |
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