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Recognition of self-peptide–MHC complexes by autoimmune T-cell receptors
T cell receptors (TCR) recognize antigenic peptides displayed by MHC molecules. Whereas T-cell recognition of foreign peptides is essential for immune defense against microbial pathogens, recognition of self-peptides can cause autoimmune disease. Structural studies of anti-foreign TCR showed remarka...
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| Asıl Yazarlar: | , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2007
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2739108/ https://ncbi.nlm.nih.gov/pubmed/17950605 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2007.08.007 |
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