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Identification of Novel Germline Polymorphisms Governing Capecitabine Sensitivity
BACKGROUND: Capecitabine, an oral 5-fluorouracil (5-FU) prodrug, is widely used in the treatment of breast, colorectal, and gastric cancers. To guide selection of patients potentially at greatest benefit of experiencing antitumor efficacy, or, alternatively, of developing toxicities, identifying gen...
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| Auteurs principaux: | , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3413892/ https://ncbi.nlm.nih.gov/pubmed/22864933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.26737 |
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