Identification of Novel Germline Polymorphisms Governing Capecitabine Sensitivity

BACKGROUND: Capecitabine, an oral 5-fluorouracil (5-FU) prodrug, is widely used in the treatment of breast, colorectal, and gastric cancers. To guide selection of patients potentially at greatest benefit of experiencing antitumor efficacy, or, alternatively, of developing toxicities, identifying gen...

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Detaylı Bibliyografya
Asıl Yazarlar: O’Donnell, Peter H., Stark, Amy L., Gamazon, Eric R., Wheeler, Heather E., McIlwee, Bridget E., Gorsic, Lidija, Im, Hae Kyung, Huang, R. Stephanie, Cox, Nancy J., Dolan, M. Eileen
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413892/
https://ncbi.nlm.nih.gov/pubmed/22864933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.26737
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