Identification of Novel Germline Polymorphisms Governing Capecitabine Sensitivity

BACKGROUND: Capecitabine, an oral 5-fluorouracil (5-FU) prodrug, is widely used in the treatment of breast, colorectal, and gastric cancers. To guide selection of patients potentially at greatest benefit of experiencing antitumor efficacy, or, alternatively, of developing toxicities, identifying gen...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: O’Donnell, Peter H., Stark, Amy L., Gamazon, Eric R., Wheeler, Heather E., McIlwee, Bridget E., Gorsic, Lidija, Im, Hae Kyung, Huang, R. Stephanie, Cox, Nancy J., Dolan, M. Eileen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413892/
https://ncbi.nlm.nih.gov/pubmed/22864933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.26737
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