Whole Genome Studies Identify Solute Carrier Transporters in Cellular Susceptibility to Paclitaxel

OBJECTIVE: Clinical use of paclitaxel is limited by variable responses and the potential for significant toxicity. To date, studies of association between variants in candidate genes and paclitaxel effects have yielded conflicting results. We sought to evaluate relationships between global gene expr...

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Autores principales: Njiaju, Uchenna O., Gamazon, Eric R., Gorsic, Lidija K., Delaney, Shannon M., Wheeler, Heather E., Im, Hae Kyung, Dolan, M. Eileen
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376193/
https://ncbi.nlm.nih.gov/pubmed/22437668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e328352f436
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