Genome-Wide Local Ancestry Approach Identifies Genes and Variants Associated with Chemotherapeutic Susceptibility in African Americans

Chemotherapeutic agents are used in the treatment of many cancers, yet variable resistance and toxicities among individuals limit successful outcomes. Several studies have indicated outcome differences associated with ancestry among patients with various cancer types. Using both traditional SNP-base...

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Autors principals: Wheeler, Heather E., Gorsic, Lidija K., Welsh, Marleen, Stark, Amy L., Gamazon, Eric R., Cox, Nancy J., Dolan, M. Eileen
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130766/
https://ncbi.nlm.nih.gov/pubmed/21755009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021920
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