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Chemotherapeutic-Induced Apoptosis – A Phenotype for Pharmacogenomics Studies
Lymphoblastoid cell lines have been used as a model system to identify genetic determinants of chemotherapeutic-induced cytotoxicity, a phenotype thought to represent cellular sensitivity to drug. However, cytotoxicity is a broad measurement encompassing cell cycle inhibition as well as cell death (...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3134538/ https://ncbi.nlm.nih.gov/pubmed/21642893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e3283481967 |
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