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Chemotherapeutic-Induced Apoptosis – A Phenotype for Pharmacogenomics Studies

Lymphoblastoid cell lines have been used as a model system to identify genetic determinants of chemotherapeutic-induced cytotoxicity, a phenotype thought to represent cellular sensitivity to drug. However, cytotoxicity is a broad measurement encompassing cell cycle inhibition as well as cell death (...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Wen, Yujia, Gorsic, Lidija K., Wheeler, Heather E., Ziliak, Dana M., Huang, R. Stephanie, Dolan, M. Eileen
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3134538/
https://ncbi.nlm.nih.gov/pubmed/21642893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e3283481967
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