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Chemotherapeutic drug susceptibility associated SNPs are enriched in expression quantitative trait loci
Pharmacogenomics has employed candidate gene studies and, more recently, genome-wide association studies (GWAS) in efforts to identify loci associated with drug response and/or toxicity. The advantage of GWAS is the simultaneous, unbiased testing of millions of SNPs; the challenge is that functional...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2889115/ https://ncbi.nlm.nih.gov/pubmed/20442332 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1001827107 |
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