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Chemotherapeutic drug susceptibility associated SNPs are enriched in expression quantitative trait loci

Pharmacogenomics has employed candidate gene studies and, more recently, genome-wide association studies (GWAS) in efforts to identify loci associated with drug response and/or toxicity. The advantage of GWAS is the simultaneous, unbiased testing of millions of SNPs; the challenge is that functional...

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Detalhes bibliográficos
Main Authors: Gamazon, Eric R., Huang, R. Stephanie, Cox, Nancy J., Dolan, M. Eileen
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889115/
https://ncbi.nlm.nih.gov/pubmed/20442332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1001827107
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