Enrichment of Cis-Regulatory Gene Expression SNPs and Methylation Quantitative Trait Loci Among Bipolar Disorder Susceptibility Variants

We conducted a systematic study of top susceptibility variants from a genome-wide association (GWA) study of Bipolar Disorder to gain insight into the functional consequences of genetic variation influencing disease risk. We report here the results of experiments to explore the effects of these susc...

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Hauptverfasser: Gamazon, ER, Badner, JA, Cheng, L, Zhang, C, Zhang, D, Cox, NJ, Gershon, ES, Kelsoe, JR, Greenwood, TA, Nievergelt, CM, Chen, C, McKinney, R, Shilling, PD, Schork, NJ, Smith, EN, Bloss, CS, Nurnberger, JI, Edenberg, HJ, Foroud, T, Koller, DL, Scheftner, WA, Coryell, W, Rice, J, Lawson, WB, Nwulia, EA, Hipolito, M, Byerley, W, McMahon, FJ, Schulze, TG, Berrettini, WH, Potash, JB, Zandi, PP, Mahon, PB, McInnis, MG, Zöllner, S, Zhang, P, Craig, DW, Szelinger, S, Barrett, TB, Liu, C
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3601550/
https://ncbi.nlm.nih.gov/pubmed/22212596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2011.174
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