Genome-Wide Association of Bipolar Disorder Suggests an Enrichment of Replicable Associations in Regions near Genes

Although a highly heritable and disabling disease, bipolar disorder's (BD) genetic variants have been challenging to identify. We present new genotype data for 1,190 cases and 401 controls and perform a genome-wide association study including additional samples for a total of 2,191 cases and 1,...

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Autores principales: Smith, Erin N., Koller, Daniel L., Panganiban, Corrie, Szelinger, Szabolcs, Zhang, Peng, Badner, Judith A., Barrett, Thomas B., Berrettini, Wade H., Bloss, Cinnamon S., Byerley, William, Coryell, William, Edenberg, Howard J., Foroud, Tatiana, Gershon, Elliot S., Greenwood, Tiffany A., Guo, Yiran, Hipolito, Maria, Keating, Brendan J., Lawson, William B., Liu, Chunyu, Mahon, Pamela B., McInnis, Melvin G., McMahon, Francis J., McKinney, Rebecca, Murray, Sarah S., Nievergelt, Caroline M., Nurnberger, John I., Nwulia, Evaristus A., Potash, James B., Rice, John, Schulze, Thomas G., Scheftner, William A., Shilling, Paul D., Zandi, Peter P., Zöllner, Sebastian, Craig, David W., Schork, Nicholas J., Kelsoe, John R.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2011
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128104/
https://ncbi.nlm.nih.gov/pubmed/21738484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002134
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