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Genome-Wide Association of Bipolar Disorder Suggests an Enrichment of Replicable Associations in Regions near Genes

Although a highly heritable and disabling disease, bipolar disorder's (BD) genetic variants have been challenging to identify. We present new genotype data for 1,190 cases and 401 controls and perform a genome-wide association study including additional samples for a total of 2,191 cases and 1,...

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Detalhes bibliográficos
Main Authors: Smith, Erin N., Koller, Daniel L., Panganiban, Corrie, Szelinger, Szabolcs, Zhang, Peng, Badner, Judith A., Barrett, Thomas B., Berrettini, Wade H., Bloss, Cinnamon S., Byerley, William, Coryell, William, Edenberg, Howard J., Foroud, Tatiana, Gershon, Elliot S., Greenwood, Tiffany A., Guo, Yiran, Hipolito, Maria, Keating, Brendan J., Lawson, William B., Liu, Chunyu, Mahon, Pamela B., McInnis, Melvin G., McMahon, Francis J., McKinney, Rebecca, Murray, Sarah S., Nievergelt, Caroline M., Nurnberger, John I., Nwulia, Evaristus A., Potash, James B., Rice, John, Schulze, Thomas G., Scheftner, William A., Shilling, Paul D., Zandi, Peter P., Zöllner, Sebastian, Craig, David W., Schork, Nicholas J., Kelsoe, John R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128104/
https://ncbi.nlm.nih.gov/pubmed/21738484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002134
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