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Trait-Associated SNPs Are More Likely to Be eQTLs: Annotation to Enhance Discovery from GWAS

Although genome-wide association studies (GWAS) of complex traits have yielded more reproducible associations than had been discovered using any other approach, the loci characterized to date do not account for much of the heritability to such traits and, in general, have not led to improved underst...

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Detalhes bibliográficos
Main Authors: Nicolae, Dan L., Gamazon, Eric, Zhang, Wei, Duan, Shiwei, Dolan, M. Eileen, Cox, Nancy J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848547/
https://ncbi.nlm.nih.gov/pubmed/20369019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000888
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