Genome-wide Meta-analysis Identifies Variants Associated with Platinating Agent Susceptibility Across Populations

Platinating agents are used in the treatment of many cancers, yet they can induce toxicities and resistance that limit their utility. Using previously published and additional world population panels of diverse ancestry totaling 608 lymphoblastoid cell lines (LCLs), we performed meta-analyses of ove...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wheeler, Heather E., Gamazon, Eric R., Stark, Amy L., O’Donnell, Peter H., Gorsic, Lidija K., Huang, R. Stephanie, Cox, Nancy J., Dolan, M. Eileen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370147/
https://ncbi.nlm.nih.gov/pubmed/21844884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2011.38
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