Genome-wide Meta-analysis Identifies Variants Associated with Platinating Agent Susceptibility Across Populations

Platinating agents are used in the treatment of many cancers, yet they can induce toxicities and resistance that limit their utility. Using previously published and additional world population panels of diverse ancestry totaling 608 lymphoblastoid cell lines (LCLs), we performed meta-analyses of ove...

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Main Authors: Wheeler, Heather E., Gamazon, Eric R., Stark, Amy L., O’Donnell, Peter H., Gorsic, Lidija K., Huang, R. Stephanie, Cox, Nancy J., Dolan, M. Eileen
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370147/
https://ncbi.nlm.nih.gov/pubmed/21844884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2011.38
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