Genome-wide Meta-analysis Identifies Variants Associated with Platinating Agent Susceptibility Across Populations

Platinating agents are used in the treatment of many cancers, yet they can induce toxicities and resistance that limit their utility. Using previously published and additional world population panels of diverse ancestry totaling 608 lymphoblastoid cell lines (LCLs), we performed meta-analyses of ove...

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Main Authors: Wheeler, Heather E., Gamazon, Eric R., Stark, Amy L., O’Donnell, Peter H., Gorsic, Lidija K., Huang, R. Stephanie, Cox, Nancy J., Dolan, M. Eileen
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370147/
https://ncbi.nlm.nih.gov/pubmed/21844884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2011.38
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