Whole Genome Studies Identify Solute Carrier Transporters in Cellular Susceptibility to Paclitaxel

OBJECTIVE: Clinical use of paclitaxel is limited by variable responses and the potential for significant toxicity. To date, studies of association between variants in candidate genes and paclitaxel effects have yielded conflicting results. We sought to evaluate relationships between global gene expr...

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Autori principali: Njiaju, Uchenna O., Gamazon, Eric R., Gorsic, Lidija K., Delaney, Shannon M., Wheeler, Heather E., Im, Hae Kyung, Dolan, M. Eileen
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376193/
https://ncbi.nlm.nih.gov/pubmed/22437668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e328352f436
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