Whole Genome Studies Identify Solute Carrier Transporters in Cellular Susceptibility to Paclitaxel

OBJECTIVE: Clinical use of paclitaxel is limited by variable responses and the potential for significant toxicity. To date, studies of association between variants in candidate genes and paclitaxel effects have yielded conflicting results. We sought to evaluate relationships between global gene expr...

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Главные авторы: Njiaju, Uchenna O., Gamazon, Eric R., Gorsic, Lidija K., Delaney, Shannon M., Wheeler, Heather E., Im, Hae Kyung, Dolan, M. Eileen
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376193/
https://ncbi.nlm.nih.gov/pubmed/22437668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e328352f436
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