Identification of Novel Germline Polymorphisms Governing Capecitabine Sensitivity

BACKGROUND: Capecitabine, an oral 5-fluorouracil (5-FU) prodrug, is widely used in the treatment of breast, colorectal, and gastric cancers. To guide selection of patients potentially at greatest benefit of experiencing antitumor efficacy, or, alternatively, of developing toxicities, identifying gen...

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Bibliografiske detaljer
Main Authors: O’Donnell, Peter H., Stark, Amy L., Gamazon, Eric R., Wheeler, Heather E., McIlwee, Bridget E., Gorsic, Lidija, Im, Hae Kyung, Huang, R. Stephanie, Cox, Nancy J., Dolan, M. Eileen
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413892/
https://ncbi.nlm.nih.gov/pubmed/22864933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.26737
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