Non-specific protein–DNA interactions control I-CreI target binding and cleavage

Homing endonucleases represent protein scaffolds that provide powerful tools for genome manipulation, as these enzymes possess a very low frequency of DNA cleavage in eukaryotic genomes due to their high specificity. The basis of protein–DNA recognition must be understood to generate tailored enzyme...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Molina, Rafael, Redondo, Pilar, Stella, Stefano, Marenchino, Marco, D’Abramo, Marco, Gervasio, Francesco Luigi, Charles Epinat, Jean, Valton, Julien, Grizot, Silvestre, Duchateau, Phillipe, Prieto, Jesús, Montoya, Guillermo
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Structural Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413129/
https://ncbi.nlm.nih.gov/pubmed/22495931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks320
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados