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Understanding the indirect DNA read-out specificity of I-CreI Meganuclease
The high DNA specificity of homing endonucleases makes them a powerful protein scaffold to engineer enzymes for genome manipulation. Understanding their molecular recognition of DNA is an important prerequisite to generate engineered enzymes able to cleave DNA in specific desired genome sites. Prote...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6035192/ https://ncbi.nlm.nih.gov/pubmed/29980759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28599-0 |
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