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Crystal Structure of the Homing Endonuclease I-CvuI Provides a New Template for Genome Modification
Homing endonucleases recognize and generate a DNA double-strand break, which has been used to promote gene targeting. These enzymes recognize long DNA stretches; they are highly sequence-specific enzymes and display a very low frequency of cleavage even in complete genomes. Although a large number o...
Zapisane w:
| Wydane w: | J Biol Chem |
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| Główni autorzy: | , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society for Biochemistry and Molecular Biology
2015
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4661390/ https://ncbi.nlm.nih.gov/pubmed/26363068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.678342 |
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