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Crystal structure of I-DmoI in complex with its target DNA provides new insights into meganuclease engineering
Homing endonucleases, also known as meganucleases, are sequence-specific enzymes with large DNA recognition sites. These enzymes can be used to induce efficient homologous gene targeting in cells and plants, opening perspectives for genome engineering with applications in a wide series of fields, ra...
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| Autori principali: | , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2579348/ https://ncbi.nlm.nih.gov/pubmed/18974222 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0804795105 |
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