Interpreting cancer genomes using systematic host perturbations by tumour virus proteins

Genotypic differences greatly influence susceptibility and resistance to disease. Understanding genotype-phenotype relationships requires that phenotypes be viewed as manifestations of network properties, rather than simply as the result of individual genomic variations(1). Genome sequencing efforts...

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Hlavní autoři: Rozenblatt-Rosen, Orit, Deo, Rahul C., Padi, Megha, Adelmant, Guillaume, Calderwood, Michael A., Rolland, Thomas, Grace, Miranda, Dricot, Amélie, Askenazi, Manor, Tavares, Maria, Pevzner, Sam, Abderazzaq, Fieda, Byrdsong, Danielle, Carvunis, Anne-Ruxandra, Chen, Alyce A., Cheng, Jingwei, Correll, Mick, Duarte, Melissa, Fan, Changyu, Feltkamp, Mariet C., Ficarro, Scott B., Franchi, Rachel, Garg, Brijesh K., Gulbahce, Natali, Hao, Tong, Holthaus, Amy M., James, Robert, Korkhin, Anna, Litovchick, Larisa, Mar, Jessica C., Pak, Theodore R., Rabello, Sabrina, Rubio, Renee, Shen, Yun, Singh, Saurav, Spangle, Jennifer M., Tasan, Murat, Wanamaker, Shelly, Webber, James T., Roecklein-Canfield, Jennifer, Johannsen, Eric, Barabási, Albert-László, Beroukhim, Rameen, Kieff, Elliott, Cusick, Michael E., Hill, David E., Münger, Karl, Marto, Jarrod A., Quackenbush, John, Roth, Frederick P., DeCaprio, James A., Vidal, Marc
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408847/
https://ncbi.nlm.nih.gov/pubmed/22810586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11288
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