Mapping of Potent and Specific Binding Motifs, GLOGEN and GVOGEA, for Integrin α1β1 Using Collagen Toolkits II and III

Integrins are well characterized cell surface receptors for extracellular matrix proteins. Mapping integrin-binding sites within the fibrillar collagens identified GFOGER as a high affinity site recognized by α2β1, but with lower affinity for α1β1. Here, to identify specific ligands for α1β1, we exa...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hamaia, Samir W., Pugh, Nicholas, Raynal, Nicolas, Némoz, Benjamin, Stone, Rachael, Gullberg, Donald, Bihan, Dominique, Farndale, Richard W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2012
Pynciau:
Glycobiology and Extracellular Matrices
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406685/
https://ncbi.nlm.nih.gov/pubmed/22654115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.353144
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