Unique charge-dependent constraint on collagen recognition by integrin α10β1

The collagen-binding integrins recognise collagen through their inserted (I) domain, where co-ordination of a Mg(2 +) ion in the metal ion-dependent site is reorganised by ligation by a collagen glutamate residue found in specific collagen hexapeptide motifs. Here we show that GROGER, found in the N...

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Vydáno v:Matrix Biol
Hlavní autoři: Hamaia, Samir W., Luff, Daisy, Hunter, Emma J., Malcor, Jean-Daniel, Bihan, Dominique, Gullberg, Donald, Farndale, Richard W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380659/
https://ncbi.nlm.nih.gov/pubmed/27569273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2016.08.010
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