Mapping of Potent and Specific Binding Motifs, GLOGEN and GVOGEA, for Integrin α1β1 Using Collagen Toolkits II and III

Integrins are well characterized cell surface receptors for extracellular matrix proteins. Mapping integrin-binding sites within the fibrillar collagens identified GFOGER as a high affinity site recognized by α2β1, but with lower affinity for α1β1. Here, to identify specific ligands for α1β1, we exa...

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Detalhes bibliográficos
Main Authors: Hamaia, Samir W., Pugh, Nicholas, Raynal, Nicolas, Némoz, Benjamin, Stone, Rachael, Gullberg, Donald, Bihan, Dominique, Farndale, Richard W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406685/
https://ncbi.nlm.nih.gov/pubmed/22654115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.353144
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