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Identification of the First Prokaryotic Collagen Sequence Motif That Mediates Binding to Human Collagen Receptors, Integrins α(2)β(1) and α(11)β(1)

Many pathogenic bacteria interact with human integrins to enter host cells and to augment host colonization. Group A Streptococcus (GAS) employs molecular mimicry by direct interactions between the cell surface streptococcal collagen-like protein-1 (Scl1) and the human collagen receptor, integrin α(...

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Bibliographische Detailangaben
Hauptverfasser: Caswell, Clayton C., Barczyk, Malgorzata, Keene, Douglas R., Lukomska, Ewa, Gullberg, Donald E., Lukomski, Slawomir
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605992/
https://ncbi.nlm.nih.gov/pubmed/18990704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806865200
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