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Sumoylation of MDC1 is important for proper DNA damage response

In response to DNA damage, many DNA damage factors, such as MDC1 and 53BP1, redistribute to sites of DNA damage. The mechanism governing the turnover of these factors at DNA damage sites, however, remains enigmatic. Here, we show that MDC1 is sumoylated following DNA damage, and the sumoylation of M...

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書目詳細資料
Main Authors: Luo, Kuntian, Zhang, Haoxing, Wang, Liewei, Yuan, Jian, Lou, Zhenkun
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3395099/
https://ncbi.nlm.nih.gov/pubmed/22635276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.158
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