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Distinct versus overlapping functions of MDC1 and 53BP1 in DNA damage response and tumorigenesis
The importance of the DNA damage response (DDR) pathway in development, genomic stability, and tumor suppression is well recognized. Although 53BP1 and MDC1 have been recently identified as critical upstream mediators in the cellular response to DNA double-strand breaks, their relative hierarchy in...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2396806/ https://ncbi.nlm.nih.gov/pubmed/18504301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200801083 |
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