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Sumoylation of MDC1 is important for proper DNA damage response

In response to DNA damage, many DNA damage factors, such as MDC1 and 53BP1, redistribute to sites of DNA damage. The mechanism governing the turnover of these factors at DNA damage sites, however, remains enigmatic. Here, we show that MDC1 is sumoylated following DNA damage, and the sumoylation of M...

詳細記述

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書誌詳細
主要な著者: Luo, Kuntian, Zhang, Haoxing, Wang, Liewei, Yuan, Jian, Lou, Zhenkun
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3395099/
https://ncbi.nlm.nih.gov/pubmed/22635276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.158
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