mTORC1 in the Paneth cell niche couples intestinal stem cell function to calorie intake

How adult tissue stem and niche cells respond to the nutritional state of an organism is not well understood. Here, we find that Paneth cells, a key constituent of the mammalian intestinal stem cell (ISC) niche, augment stem cell function in response to calorie restriction (CR). CR acts by reducing...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Yilmaz, Ömer H., Katajisto, Pekka, Lamming, Dudley W., Gültekin, Yetis, Bauer-Rowe, Khristian E., Sengupta, Shomit, Birsoy, Kivanc, Dursun, Abdulmetin, Yilmaz, V. Onur, Selig, Martin, Nielson, G. Petur, Mino-Kenudson, Mari, Zukerberg, Lawrence, Bhan, Atul, Deshpande, Vikram, Sabatini, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3387287/
https://ncbi.nlm.nih.gov/pubmed/22722868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11163
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados