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Conditional expression of oncogenic K-ras from its endogenous promoter induces a myeloproliferative disease
Oncogenic ras alleles are among the most common mutations found in patients with acute myeloid leukemia (AML). Previously, the role of oncogenic ras in cancer was assessed in model systems overexpressing oncogenic ras from heterologous promoters. However, there is increasing evidence that subtle dif...
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| Hlavní autoři: | , , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Clinical Investigation
2004
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC338267/ https://ncbi.nlm.nih.gov/pubmed/14966562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200420476 |
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