טוען...
Oncogenic K-ras cooperates with PML-RARα to induce an acute promyelocytic leukemia-like disease
Most patients with acute promyelocytic leukemia (APL) express PML-RARα, the fusion product of t(15;17)(q22;q11.2). Transgenic mice expressing PML-RARα develop APL with long latency, low penetrance, and acquired cytogenetic abnormalities. Based on observations that 4% to 10% of APL patients harbor on...
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| Main Authors: | , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
© 2006 by The American Society of Hematology
2006
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| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1895511/ https://ncbi.nlm.nih.gov/pubmed/16675706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-04-015040 |
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