A bcr-3 isoform of RARα-PML potentiates the development of PML-RARα-driven acute promyelocytic leukemia

Acute promyelocytic leukemia (APML) most often is associated with the balanced reciprocal translocation t(15;17) (q22;q11.2) and the expression of both the PML-RARα and RARα-PML fusion cDNAs that are formed by this translocation. In this report, we investigated the biological role of a bcr-3 isoform...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Pollock, Jessica L., Westervelt, Peter, Kurichety, Arun K., Pelicci, Pier Giuseppe, Grisolano, Jay L., Ley, Timothy J.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1999
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24780/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10611345/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.26.15103
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