Cell death induction by the acute promyelocytic leukemia-specific PML/RARα fusion protein

PML/RARα is the abnormal protein product generated by the acute promyelocytic leukemia-specific t(15;17). Expression of PML/RARα in hematopoietic precursor cell lines induces block of differentiation and promotes survival. We report here that PML/RARα has a potent growth inhibitory effect on all non...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Ferrucci, Pier Francesco, Grignani, Francesco, Pearson, Mark, Fagioli, Marta, Nicoletti, Ildo, Pelicci, Pier Giuseppe
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1997
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23524/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9380732/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.20.10901
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