Structurally Diverse GABA Antagonists Interact Differently with Open and Closed Conformational States of the ρ(1) Receptor

[Image: see text] Ligands acting on receptors are considered to induce a conformational change within the ligand-binding site by interacting with specific amino acids. In this study, tyrosine 102 (Y102) located in the GABA binding site of the ρ(1) subunit of the GABA(C) receptor was mutated to alani...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Yamamoto, Izumi, Carland, Jane E., Locock, Katherine, Gavande, Navnath, Absalom, Nathan, Hanrahan, Jane R., Allan, Robin D., Johnston, Graham A. R., Chebib, Mary
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2012
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369803/
https://ncbi.nlm.nih.gov/pubmed/22860195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn200121r
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados