Laddar...

Inhibition of factor XI activation attenuates inflammation and coagulopathy while improving the survival of mouse polymicrobial sepsis

Severe bacterial sepsis often leads to a systemic procoagulant and proinflammatory condition that can manifest as disseminated intravascular coagulation, septic shock, and multiple organ failure. Because activation of the contact proteases factor XII (FXII), prekallikrein, and factor XI (FXI) can tr...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Tucker, Erik I., Verbout, Norah G., Leung, Philberta Y., Hurst, Sawan, McCarty, Owen J. T., Gailani, David, Gruber, András
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Hematology 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367876/
https://ncbi.nlm.nih.gov/pubmed/22442348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-10-386185
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!