Inhibition of Factor XII-Mediated Activation of Factor XI Provides Protection Against Experimental Acute Ischemic Stroke in Mice

Blood coagulation factor XI (FXI) is an established risk factor for acute ischemic stroke (AIS) and thrombosis, but is also needed for normal hemostasis. Contact factor XII (FXII), an upstream activator of FXI, also contributes to experimental stroke, but is not required for hemostasis. We investiga...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Leung, Philberta Y., Hurst, Sawan, Berny-Lang, Michelle A., Verbout, Norah G., Gailani, David, Tucker, Erik I., Wang, Ruikang K., McCarty, Owen J. T., Gruber, András
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637928/
https://ncbi.nlm.nih.gov/pubmed/23634198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12975-012-0186-5
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados