Factor XI contributes to myocardial ischemia-reperfusion injury in mice

Inhibiting contact activation of factor XI during reperfusion of acute myocardial ischemia reduces infarct size in mice. Factor XII/XI contact axis inhibition may improve the outcome of coronary artery recanalization in acute myocardial infarction.

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Bibliografske podrobnosti
izdano v:Blood Adv
Main Authors: Lorentz, Christina U., Verbout, Norah G., Cao, Zhiping, Liu, Lijuan, Hinds, Monica T., McCarty, Owen J. T., Ivanov, Ivan, Tucker, Erik I., Gailani, David, Gruber, András
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2018
Teme:
Stimulus Report
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5787867/
https://ncbi.nlm.nih.gov/pubmed/29365314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017004879
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