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Survival Advantage of Coagulation Factor XI-Deficient Mice during Peritoneal Sepsis

Anticoagulation is a rational approach to the treatment of sepsis-associated consumptive coagulopathy, but its application is limited because of the risk of excessive bleeding. Factor XI (FXI) contributes substantially to pathological blood coagulation (thrombosis), whereas it contributes only modes...

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Detalhes bibliográficos
Main Authors: Tucker, Erik I., Gailani, David, Hurst, Sawan, Cheng, Qiufang, Hanson, Stephen R., Gruber, András
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654284/
https://ncbi.nlm.nih.gov/pubmed/18491973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/589514
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