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Isolation of phosphatidylethanolamine as a solitary cofactor for prion formation in the absence of nucleic acids
Infectious prions containing the pathogenic conformer of the mammalian prion protein (PrP(Sc)) can be produced de novo from a mixture of the normal conformer (PrP(C)) with RNA and lipid molecules. Recent reconstitution studies indicate that nucleic acids are not required for the propagation of mouse...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3365173/ https://ncbi.nlm.nih.gov/pubmed/22586108 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1204498109 |
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