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Isolation of phosphatidylethanolamine as a solitary cofactor for prion formation in the absence of nucleic acids
Infectious prions containing the pathogenic conformer of the mammalian prion protein (PrP(Sc)) can be produced de novo from a mixture of the normal conformer (PrP(C)) with RNA and lipid molecules. Recent reconstitution studies indicate that nucleic acids are not required for the propagation of mouse...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3365173/ https://ncbi.nlm.nih.gov/pubmed/22586108 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1204498109 |
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