Isolation of phosphatidylethanolamine as a solitary cofactor for prion formation in the absence of nucleic acids

Infectious prions containing the pathogenic conformer of the mammalian prion protein (PrP(Sc)) can be produced de novo from a mixture of the normal conformer (PrP(C)) with RNA and lipid molecules. Recent reconstitution studies indicate that nucleic acids are not required for the propagation of mouse...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Deleault, Nathan R., Piro, Justin R., Walsh, Daniel J., Wang, Fei, Ma, Jiyan, Geoghegan, James C., Supattapone, Surachai
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2012
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365173/
https://ncbi.nlm.nih.gov/pubmed/22586108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1204498109
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