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Phosphatidylethanolamine as a prion cofactor: Potential implications for disease pathogenesis

Mammalian prions with significant levels of specific infectivity can be formed in vitro from mixtures of prion protein (PrP) and cofactor molecules, but not from PrP alone. We recently isolated and identified the essential membrane phospholipid phosphatidylethanolamine (PE) as an endogenous cofactor...

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Bibliografische gegevens
Hoofdauteur: Supattapone, Surachai
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Landes Bioscience 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510863/
https://ncbi.nlm.nih.gov/pubmed/22895101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.21826
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