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Phosphatidylethanolamine as a prion cofactor: Potential implications for disease pathogenesis
Mammalian prions with significant levels of specific infectivity can be formed in vitro from mixtures of prion protein (PrP) and cofactor molecules, but not from PrP alone. We recently isolated and identified the essential membrane phospholipid phosphatidylethanolamine (PE) as an endogenous cofactor...
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| Hovedforfatter: | |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Landes Bioscience
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3510863/ https://ncbi.nlm.nih.gov/pubmed/22895101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.21826 |
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