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Synthesis of High Titer Infectious Prions with Cofactor Molecules

Recently, synthetic prions with a high level of specific infectivity have been produced from chemically defined components in vitro. A major insight arising from these studies is that various classes of host-encoded cofactor molecules such as phosphatidylethanolamine and RNA molecules are required t...

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Autor principal: Supattapone, Surachai
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4106305/
https://ncbi.nlm.nih.gov/pubmed/24860097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R113.511329
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